Some facial paralysis needs antiviral treatment

Some facial paralysis needs antiviral treatment

One of the etiology of facial paralysis is the theory of viral infection. The viruses considered to be related to Belle’s facial paralysis and researched are: herpes simplex virus, varicella-zoster virus, cytomegalovirus, EB virus, adenovirus and other viruses.

Many scholars are now more likely to notice that viral infections, especially herpes simplex virus infections, are the cause of Bell’s facial paralysis; Bell’s facial paralysis is caused by latent virus activation.

  Clinically used antiviral drugs are: ribavirin and acyclovir.

  (1) Aciclovir tablets (9- (2-hydroxyethoxymethyl) -guanine) have a high effect on herpes simplex virus (HSV) type I and herpes zoster virus Ⅱ.

After acyclovir enters herpes-infected cells, it competes with deoxynucleosides for viral thymidine kinase kinase or cell kinase. The drug is phosphorylated into activated acyclic bird phosphate triphosphate, which serves as a substrate for viral DNA replication and deoxyguanine phosphate.Phosphate competes with viral DNA polymerase, thereby inhibiting virus synthesis and showing antiviral efficacy.

Usage: Oral, 2 tablets each time, every 3 hours, 5 times a day, even for 5-7 days.

  (2) Ribavirin (ribavirin injection) This drug has inhibitory effects on a variety of RNA and DNA viruses and can prevent virus replication.

Usage: Intravenous infusion or intramuscular injection, 10-15mg per kg of body weight per day, divided into two injections, continuous use for 5-7 days as a course of treatment.